The Newcotiana project aims to modify the composition and, therefore, the use we make of tobacco plants, enriching them with substances of high added value. For this, the Newcotiana scientists will employ highly precise breeding technologies, such as the CRISPR technique, and apply them to breeding cultivated tobacco and its relative species N. benthamiana as improved biofactories. In this way, it is intended to revalue the traditional cultivation of tobacco and, at the same time, to improve our manufacturing capacity for health-related bioproducts, such as vaccines, antibodies and other important small molecules with health-promoting properties.